I remember one morning a few years ago, a young and handsome guy walked into my clinic. At first, he said that the joint was painful and cold. After the film was taken, it was found that there was a problem with the sacroiliac joint. Later, I checked it carefully, and did a test, and finally diagnosed as ankylosing spondylitis. I still remember that the young patient was frustrated and nervous when holding the HLA-B27 test sheet and asked tremblingly: Doctor, do I have a disease called "undead cancer".

　　Ankylosing spondylitis aka Marie -strümpell disease, Von Bechterew disease, rheumatoid spondylitis, deformity spondylitis, rheumatoid central type, etc., are now called AS. It is characterized by multiple males, the onset of young adults, inflammation and ossification of the spine and ligaments of the waist, neck, thoracic spine, and sacroiliac joints of the patient, hip joints are often involved, and inflammation may also occur in other surrounding joints. The disease is generally negative for rheumatoid factor, so it is all seronegative spondylopathy with Reiter syndrome, psoriatic arthritis, enteric arthritis and so on.

　　Ankylosing spondylitis is a very old disease. Humans have been fighting it for thousands of years. Because the previous treatment is very unsatisfactory, patients often fall into severe, unrelieved pain, and Doctors are usually helpless, so this disease was once called "undead cancer".

　　 Since the beginning of the new century, with the continuous emergence of new technologies and new materials in the medical field, various therapeutic methods have gradually exerted their power, from physical therapy, drug therapy, immunotherapy, biological therapy to surgical treatment... Now, the "cancer" of ankylosing spondylitis not only does not die, but can also be relieved for a long time.