The key to bone metastasis is to find the primary lesion, depending on whether the primary tumor is cured or not, but if most of the tumors have already undergone bone metastasis, the stage is late and the treatment effect may be poor .

　　 In fact, in many people’s ideas In China, the metastasis of the tumor is at an advanced stage, and it is weak. However, with the progress of treatment measures, patients with metastases may also survive for a long time.

　　The treatment of bone metastases is to reduce symptoms, prevent fractures and other related complications, improve quality of life and prolong survival. The main treatment methods for malignant tumor bone metastasis include drug therapy, radiotherapy, and surgical treatment.

　　One drug therapy is the basis

　　 Chemotherapy is indispensable for controlling metastasis. For chemotherapy-sensitive tumors, such as small cell lung cancer, systemic chemotherapy has a certain effect on the primary and metastatic foci of solid tumors, but it is not effective for the pain relief of bone metastases in some patients.

　　Bisphosphonate drugs treat most bone metastases are osteolytic, and the trabecular bone cortex is damaged. Bisphosphonates are a class of specific drugs for the treatment of osteolytic bone metastases and hypercalcemia. Bisphosphonates have been developed to the third generation. Take ibandronate and zoledronic acid as representatives. Taking zoledronic acid as an example, the conventional dosage is once every 3-4 weeks, and it should be used for at least half a year.

　　Two options for radiotherapy

　　Re-hardening osteolytic lesions, reducing tumor infiltration and compressing nerves, thereby reducing pain. The most commonly used is external irradiation, which uses X-rays and gamma rays to reach the lesions. The gamma knife is often used to locate the lesions using stereotactic technology, using the Ono cluster to irradiate the target area with a single large-dose non-coplanar rotation, resulting in necrosis of the diseased tissue. A technology.

　　Three proper surgical procedures are helpful

　　Thirty years ago, if a doctor tried to operate on a patient with bone metastases, it would definitely suffer In terms of questioning, it is even considered "Hu Zhi". However, in recent years, case-control studies and retrospective studies have confirmed that reasonable surgery will treat and prevent pathological fractures, relieve spinal cord compression, relieve compressive pain caused by bone metastases, improve patient quality of life, and provide opportunities for comprehensive quality.

　　Surgical indications for bone metastases include: uncontrollable pain, pathological fractures of long bones, neurological symptoms caused by spinal metastases no more than 3 weeks, and continued neurological damage is expected to survive longer than 3 months It is estimated that the pelvic lesions will survive for more than 4 months after radiotherapy and chemotherapy. The isolated bone metastases that have been cured of the original lesion and the general condition are good. They can tolerate surgical trauma and anesthesia.