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What are the chemotherapy options for bowel cancer?

BY Polly Steele 2020-07-24

The side effects during chemotherapy are relatively large. The most obvious are gastrointestinal reactions, hair loss, and leukopenia. Chemotherapy can inhibit the hematopoietic function of bone marrow cells, and white blood cells will decline sharply. Especially for the elderly who are already weak. Get chemotherapy.

Even so, there is often no change A good way, so chemotherapy is also a common method. For patients with bowel cancer, chemotherapy is a commonly used method, but according to the condition of each patient, the chemotherapy regimen is also different. 1. Oral fluorouracil regimen. 2. Oxaliplatin joint 5fu/lv plan. Oxaliplatin (oxaliplatin) is the third generation of platinum drugs, mainly by directly inhibiting the synthesis of DNA to play a role in suppressing tumors. Because its synergy with 5fu is reflected in the field of metastatic colorectal cancer, its role in adjuvant chemotherapy has received much attention. 3. irinotecan joint 5fu/lv plan. Irinotecan (cpt11) is a semi-synthetic derivative of natural camptothecin. It inhibits the replication and transcription of DNA by inhibiting topoisomerase i, and thus exerts an inhibitory effect on tumors. Although it has shown considerable efficacy in the treatment of metastatic colorectal cancer, either as a single drug or in combination with 5fu/lv, the results of the three clinical trials so far have not been satisfactory in terms of adjuvant chemotherapy. Ginsenoside Rh2, as a Chinese medicine for adjuvant therapy, can effectively reduce the side effects caused by radiotherapy and chemotherapy. It is recommended to use it after chemotherapy. In addition, ginsenoside Rh2 capsule products with a content of 16.2% can be more effectively absorbed by cancer patients. If it is unilateral, the effect is better.

The treatment method generally adopted by patients with bowel cancer, surgical resection is the preferred treatment method, postoperative adjuvant chemoradiation and traditional Chinese medicine treatment. If the elderly have weak physical function and belong to patients with advanced rectal cancer, it is difficult to tolerate Surgery and radiotherapy and chemotherapy can also be treated simply with traditional Chinese medicine, which has a positive effect on improving symptoms and improving quality of life. Studies have confirmed that the proliferation of cancer cells after treatment with ginsenoside Rh2 (fate) with a content of about 16% of ginseng extract is significantly reduced, which means that ginsenoside Rh2 can inhibit the growth of cancer cells or directly kill cancer cells. , Make the tumor tissue shrink or disappear. Therefore, ginsenoside Rh2 can cooperate with surgery, radiotherapy and chemotherapy to kill cancer cells.

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