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What is adjuvant chemotherapy

BY Iris Wheatley 2020-07-24

  What is adjuvant chemotherapy? Chemotherapy is a common method for treating malignant tumors, but it is not a panacea. In other words, not all cancer cells are sensitive to chemotherapy drugs, so for some insensitive cancer types, Chemotherapy can not be used as the main treatment method, only adjuvant therapy can be used to achieve the purpose of prolonging the life of patients.

  carried out on body tumors Before and after surgical treatment and radiotherapy, chemotherapy is used to shrink the primary tumor, and at the same time may eliminate the remaining small metastatic lesions, reduce the chance of tumor recurrence and metastasis, and improve the cure rate. The chemical drug treatment becomes adjuvant chemotherapy.

   The purpose of adjuvant chemotherapy is to kill small lesions that cannot be removed by surgery, reduce recurrence, and improve survival. Therefore, patients with tumors with a high probability of metastasis and recurrence should receive chemotherapy after surgery. The traditional concept is that for colon cancer, only stage III chemotherapy can prolong survival and is an indication for chemotherapy; while for rectal cancer, stage I does not require chemotherapy, and stage II and III are best after chemotherapy and radiotherapy. .

  Michael et al. studied the potency ratio of various colorectal cancer chemotherapy regimens, and found that it is most reasonable to perform adjuvant chemotherapy for all stage II and III colorectal cancer. The length of the chemotherapy period involves issues such as drug treatment, price, effects, and quality of life. Most effective treatments are active treatment of colorectal cancer for 1 year.

  Single chemotherapeutic drugs are less effective in treating colorectal cancer, and most of them are partial remission (PR); the application of combined chemotherapy drugs can significantly improve the median survival time and prolong the life of patients. In recent years, in improving the efficacy of 5-Fu for colorectal cancer, the most innovative and active research is the use of biological regulators to improve the anti-tumor activity of 5-Fu, and on this basis, continuous innovation, achieved Great progress has been made.

  Because there is a probability of tumor recurrence, regular re-examination after surgery. The time and location of the re-examination is very important. It is recommended that patients go to a cancer specialist hospital, at least the oncology department of a general hospital. Please ask an experienced oncologist to help complete the necessary examinations. The examination should be performed every 6 months within 2 years after surgery. Once a year after 2 years.

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