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Is hypothalamic hamartoma inherited in children?

BY Carol Carey 2019-12-07

  Children''s hypothalamic hamartoma is related to genetic genetic factors. It is a congenital abnormality of brain tissue development and is a genetic disease controlled by multiple genes. However, in addition to this, the disease may also be caused by the misalignment of the glomerular brain plate during pregnancy, or because it has diencephalon epilepsy, and pregnant women''s bad habits during pregnancy can also be a cause.

   mentioned hypothalamic hamartoma , Probably most people will feel relatively unfamiliar. But in the clinical aspect, the disease has a certain possibility of morbidity in children, and once the disease will cause abnormal behavior and adverse symptoms such as epilepsy, it is necessary to find and induce the factors in time. So, are children''s hypothalamic hamartoma inherited?
  Is the children’s hypothalamic hamartoma inherited?
  Children’s hypothalamic hamartoma is a congenital disease, which is caused by abnormal development of brain tissue. And after a large number of clinical case studies, it is found that the hypothalamic hamartoma in children does have genetic possibility, which may be a polygenic inherited disease. However, because the disease is relatively rare, children with a family history account for only a small part, perhaps less than one-tenth.
  Second, other causes of hypothalamic hamartoma in children
  1. Dislocation of globular brain plate
  hypothalamic hamartoma In addition to genetic genetic factors, it may also be caused by misalignment of the glomerular brain board. Specifically, the hypothalamic hamartoma originates from the papillary body or gray nodules of the child, and it will develop when a small globular brain plate is formed between 35-40 days of the pregnancy response. Once the normal brain tissue is misaligned, it will remain in the hypothalamus, and the normal brain tissue can form an odor mass, which can lead to disease.
  2. Diencephalon epilepsy
  If children themselves have diencephalon epilepsy, the possibility of suffering from upper and lower thalamus hamartomas will increase greatly. Mainly due to the epilepsy of the midbrain, the peripheral limbic system will be damaged and the neuroendocrine function will be impaired, resulting in the formation of small secretory particles around the nucleus of neurons. If it is not released in time, it may occur.
  3. Bad habits during pregnancy
  For pregnant mothers who have unhealthy living habits during pregnancy, the next generation will have a high chance of developing hypothalamic hamartoma. Especially when chronically stimulated by radiation and polluted air, the hypothalamus and brain tissue development are prone to abnormalities, which can lead to the presence of ectopic brain tissue at the gray nodules, which in turn can cause upper and lower thalamus hamartomas.

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