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What is the prognosis of rectal cancer t3n0m0

BY Iris Wheatley 2020-07-30

  T3n0m0 This is the pathological stage of colon cancer, which is in stage 2, a total of 4 stages, which is equivalent to the middle stage. The earlier the stage, the better the prognosis. Rectal cancer involves neoadjuvant radiotherapy and chemotherapy, TME and CRM, etc., and must distinguish between rectal cancer and colon cancer. Originoo_39036_57954459_l.jpg

The NCCN guidelines believe that rectal cancer is a rectal cancer that occurs within 12 cm from the anal verge by hard tube enteroscopy. However, ESMO guidelines believe that the tumor is less than 15cm away from the anal margin. Therefore, there is a clear difference between them. If the tumor has a longitudinal diameter of 3 cm, ESMO guidelines believe that tumors 18 cm from the anal margin are also rectal cancer.

  Although our surgery has distinguished low rectal cancer (within 5 cm from the dentate line), median rectal cancer (within 5-10 cm from the dentate line) and high rectal cancer (from the dentate line) Line 10-15 cm). However, at present it is not very reasonable.

   1. In terms of anatomical characteristics, the large intestine above 12cm is more like a colon, with a mesentium than a rectum;

   2. In terms of biological characteristics, above 12cm The recurrence of the large intestine resembles the colon rather than the rectum;

  3. In terms of tumor therapy: it is generally considered that the rectum of radiotherapy is preferably below the sacral promontory, because the position of the rectum below is fixed and the position is relatively Low is not easy to damage the small intestine.

   Rectal cancer t3n0m0. At the same time, the treatment of low and middle rectal cancer involves TME, CRM, etc. It also needs a clear and unified concept. There are also many divergences in China.

  1. The clinical operation consensus of MDT for liver metastasis of colorectal cancer is that the lower edge of the tumor is within 10 cm of the dentate line, and the cancer is retroperitoneal.

   2. Tumors that develop from the anal verge to the rectum of 10 cm.

  3. Cancer within 10 cm from the dentate line, with the peritoneum reflexed.

From the perspective of surgical TME treatment and CRM evaluation, we believe that low and medium rectal cancer should be defined as cancers below the peritoneal reflex. However, the individual position of the peritoneal reflex is quite different, and the position of women is lower than that of men. According to foreign reports, women''s peritoneal reflexes are 9 cm away from the anal margin on average, and men are 9.7 cm away from the anal margin. Our anatomy believes that the peritoneum is about 7-8 cm from the anal verge.

   First of all, it should be clear what part of the tumor is, and most of the three stage tumors are mid-advanced tumors. Rectal cancer is formed by malignant transformation of rectal tissue cells. With the improvement of quality of life, the incidence of rectal cancer increases year by year, and the incidence of colorectal cancer (colon cancer + rectal cancer) is reported to be ranked third. The first two are lung cancer and gastric cancer. In principle, for stage III rectal cancer, chemotherapy should be performed as long as conditions permit. Symptomatic treatment is required during treatment. You can also use radiotherapy, biological therapy, traditional Chinese medicine treatment and so on.

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