Speaking of the repeated vomiting of small babies, many people immediately think of the word "disease from the mouth", and people often associate vomiting with digestive system diseases. Such as gastritis, esophageal reflux, dyspepsia, acute gastroenteritis and other common diseases of the digestive system, this is not wrong, but among the causes of children''s vomiting, the relationship between vomiting and food allergy is the most easily overlooked.

　　 went to the clinic this morning, from outside A small baby who had repeated vomiting came from the county. The parents of the child complained that the child always loves to vomit after birth. The local hospital doctor recommended to go to Xi''an to have a stomach examination. I see the child is in good spirits, but the eczema on the head is obvious. Combined with the significant increase in the proportion of eosinophils in the child''s blood routine examination, I concluded that the child''s vomiting and the child''s milk protein allergy may have a great relationship. (The child ate very little human milk after birth, mainly formula milk.)

　　I suggest that the child should not choose the stomach examination first, because either the gastroscope or X-ray barium meal fluoroscopy Such a small baby is at risk, and it can be treated experimentally, and if it is not possible, further examinations will be performed. When I told my parents that the child might be vomiting caused by milk protein allergy, the parents were confused and doubted.

　　Is milk still allergic? My child does not experience allergies after eating? In many people’s inherent knowledge, allergies should be caused by a rash immediately after eating a certain food. In fact, only severe acute allergies often occur, and chronic allergies, even some doctors (non-national allergy professional doctors), may not know.

　　Chronic food allergy (also called food intolerance) is one of the common clinical diseases and the earliest allergy problems in babies.The clinical symptoms caused by it are diverse, involving the skin, digestive tract, Multiple organs and systems such as the respiratory tract and even the nervous system. In recent years, with the change of living environment and lifestyle, the phenomenon of frequent vomiting of infants caused by food protein allergy has attracted people''s attention. The incidence of food protein allergic diseases with vomiting as the main manifestation has also shown an upward trend. I have investigated (infants from 3 months to one year old) 32 infants with vomiting as the main manifestation. The food intolerance test is the serum food-specific IgG test. All children meet the following conditions: 1) The main symptoms are frequent vomiting, Partially accompanied by diarrhea, bloody stools, eczema, and slow growth; 2) upper gastrointestinal endoscopy suggests gastric and duodenal mucosal lesions; 3) food intolerance test is intolerant to one or more food proteins; 4 ) Food

　　Avoidance test or provocation test was positive.

　　These children all have vomiting as the main clinical manifestation, which often occurs after eating and becomes non-ejective, ranging from 2 to 6 times a day. The vomit is milk and milk clot, without Bile and fecal juice were not accompanied by crying and restlessness before and after vomiting. I had been diagnosed with acute gastritis or gastroesophageal reflux. No significant improvement was given to gastrointestinal motility drugs. 10 cases with diarrhea, stools were yellow mushy or egg-like stools, 3 to 5 times a day, varying the amount of each time, had been diagnosed with diarrhea, intestinal mucosal protection agent, micro-ecological preparation treatment did not significantly improve; bloody stools 2 cases of babies with bloody stools or a small amount of fresh blood, symptomatic hemostasis and other treatments were not good; 10 of them were accompanied by eczema, most of which were found on the head, face, and trunk, buttocks, manifested as wind-like rash, itching, and severe Patients with eczema showed exudation and crusting, and there was no obvious effect of external medicine treatment in the dermatology clinic; body weight growth was slow or no growth, and subcutaneous fat gradually decreased in 1 case. Antibiotic treatment was repeatedly applied in the diagnosis and treatment of the foreign hospital, which was invalid.

　　Milk allergy is the most common food allergy problem in infants. The incidence rate in infants is about 0.3％~7.5％. Non-IgE-mediated food allergic reactions

　　 is known as food intolerance, which is a current research hotspot at home and abroad. The mechanism of food intolerance is due to some or more of the immune system entering the body

　　 Foods are regarded as harmful substances, thus generating excessive protective immune responses against these substances. Produces food-specific antibody IgG. Specific IgG antibodies form immune complexes with food particles (type III allergy), causing inflammation in all tissues and manifesting as symptoms and diseases of various systems throughout the body. The effects of food intolerance in infants can be found throughout the body and in various clinical manifestations. 5％~15％Suspected symptoms of children with milk allergies may accumulate one or

　　multiple organs, manifested as skin itching, urticaria, eczema, etc.; digestive system can manifest as vomiting , Diarrhea, flatulence, intestinal cramps, etc.; breathing

　　 inhalation system can be manifested as runny nose, sneezing, stuffy nose, cough, wheezing, and even anaphylactic shock. Symptoms or diseases like these often have a serious impact on the growth and development of children with

　　. And because of the lack of effective diagnostic methods, clinical diagnosis is ignored and the diagnosis is delayed.

　　 For infants with food allergies or intolerance, breastfeeding rarely occurs, but nowadays, the market has introduced a large number of milk products, wrong feeding concepts and premature use of milk powder, and excessive dependence Misconceptions such as milk powder psychology have caused more and more children to rely on milk powder prematurely for allergy symptoms and allergic diseases.

　　 For infants who cannot breastfeed or enter the transition period, they must choose an appropriate allergic or hypoallergenic formula based on the risk of the infant’s allergic disease. As we all know, blind fasting of heterosexual proteins in children with milk allergies can cause malnutrition and slow growth in children, leading to unsustainable disease progression and a vicious cycle. However, with the gradual improvement of formula milk powder processing technology, the occurrence of the above phenomenon has been greatly reduced . At present, the European Society of Pediatric Allergy and Clinical Immunology and the American Academy of Pediatric Nutrition Society’s standards for hypoallergenic milk are: The basis of this formula is the hydrolysis of milk protein. The peptide fragments after hydrolysis are small enough. In the milk allergic infant group, 90％ ; The object can tolerate.

　　I hope that more and more doctors and parents will learn more about food allergy-related knowledge, so that allergic children can take fewer detours.